Journey of a Late Blooming Biochemical Neuroscientist

Journey of a late blooming biochemical neuroscientist.

I graduated from tuition-free College of the City of New York (CCNY) in 1933. At that time the country was in the depths of the Great Depression, and there were few positions available for City College graduates. Its students were mainly children of immigrants who were bright and highly motivated. CCNY graduates included eight future Nobel Prize awardees and several distinguished biochemists. A...

Boosting the Late-Blooming Boy

CONTEXT: The indications for use of growth hormone (GH) have broadened with the availability of unlimited recombinant human growth hormone (rhGH). The FDA's approval for use of growth hormone in GH-sufficient patients with idiopathic short stature includes some children with constitutional delay of growth and puberty (CGD), a normal growth pattern variation which includes delayed puberty and pr...

The case of galantamine: repurposing and late blooming of a cholinergic drug

Galantamine is a reversible inhibitor of cholinesterases and an allosteric modulator of neuronal nicotinic acetylcholine receptors which restores reduced cholinergic tone in the central and peripheral nervous system. Characterized in the early 1950s in Bulgaria, it saw limited use for paralytic and neuropathic conditions until the cholinergic hypothesis of Alzheimer's disease opened totally new...

Self-incompatibility Studies of Some Iranian Late-Blooming Almonds and Pollen Source Effect on Some Characteristics of Nuts

The objective of this experiment was to evaluate self-compatibility of two late blooming almond cultivars and identification and introduction of suitable pollinizers from late flowering genotypes, and evaluation of pollen source effect on fruit characteristics to earn high quality nuts for Iranian almond industry. This experiment was carried out in order to determine the best pollinizer for two...

Tales of a Stone Age Neuroscientist.